In vivo evidence for dendritic cell lysis by NK cells
نویسنده
چکیده
By using an experimental model of anticancer vaccination, we have recently lent support to the assumption, so far only sustained by in vitro data, that natural killer cells can restrain less immunogenic, allegedly tolerogenic, dendritic cells (DCs). This in vivo selection of immunogenic DCs appears to depend on perforin and to be associated with a more protective tumor-specific T lymphocyte response.
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2012